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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11942 | MAP4K4-IN-3 | Compound 17 | MAPK |
MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase. | |||
T5483 | DMX-5804 | DMX-5084 | MAPK |
DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice. | |||
T9523 | TGFβRI-IN-3 | TGF-beta/Smad | |
TGFβRI-IN-3 inhibits TGFβR1 with an IC 50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 is a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology [1]. |